COVID-19

[grunthy]

https://clinicaltrials.gov/ct2/show/NCT ... w=2&rank=1

Clinical trial on if facemasks do reduce chance of getting covid.

[nocera]

By the way, the bar owner who planned tomorrow's protest over the ACHD's decision to close indoor bars had to close his bar due to an employee testing positive.

[slappybrown]

https://www.cnbc.com/2020/07/01/pfizer- ... trial.html

The trial evaluated 45 people. Each participant received 10, 30 or 100 microgram doses of the vaccine or a placebo.

The company said one of its four coronavirus vaccine candidates produced neutralizing antibodies, which researchers believe is necessary to build immunity to the virus, in all participants who received two of the 10 or 30 microgram doses after 28 days, according to the preliminary data, which was posted in a paper released on MedRXiv. The company said the levels of neutralizing antibodies were 1.8 to 2.8 times higher than in recovered Covid-19 patients.

After 28 days, all participants in the two lower dose groups had significant levels of binding antibodies, the company said.

Pfizer said the vaccine was generally well tolerated, though the experimental vaccine caused fever in some patients, especially for those who were in the 100 microgram group. Most patients reported pain at the injection site, which was mild to moderate, the company said, except in one of 12 subjects who received a 100 microgram dose, which was severe.

The findings posted Wednesday have not been peer-reviewed yet.

[count2infinity]

I'd tolerate a bit of fever and injection site pain to potentially have immunity.

[MR25]

Out of curiosity: is 28 days considered "long-term" in determining if there's any long-term side effects of a vaccine?

Like, if there was some potentially life-altering side effect would it have shown up in this trial?

[NTP66]

I'd tolerate a bit of fever and injection site pain to potentially have immunity.

[nocera]

I'm obviously not anti-vaxx, but I have to be honest, a vaccine that has been accelerated through development this quickly does make me nervous. I probably wouldn't even be able to be among the first to get it anyway (I assume the first few batches will be reserved for high risk folks), but I will definitely be reviewing the studies like crazy before I get it. There's also the fact that the current administration hasn't exactly handled the pandemic well, and they would be the first to tout an American-made vaccine. I worry that they'd push anything through to just have that talking point during election time.

[count2infinity]

I'm sorry... are you suggesting that something that came out of "operation warp speed" might have something that was overlooked?

[slappybrown]

This was just the stage 1 trial. They are behind other vaccine candidates (Moderna is entering late stage (stage 3) trials this month) and stage 2 for this one won't start till later this month according to the article.

[MalkinIsMyHomeboy]

"we need 12 months"

"you get 3; I don't care how you get it done, just do it"

[Gaucho]

[King Colby]

Trust modern medicine. Theyre not gonna put out something harmful because trump said so. Thats conspiracy theory stuff. More likely outcome is they put out something that doesn't work that well.

[shafnutz05]

I'm obviously not anti-vaxx, but I have to be honest, a vaccine that has been accelerated through development this quickly does make me nervous.

Yeah, I am in the same boat. And I say this as someone that got the smallpox vaccine when I was active duty, and nothing could be worse than what that was like.

I can only imagine the shtstorm if they were to make it mandatory.

[King Colby]

can't make it mandatory but hopefully schools and daycares require it. And hospitals for health care workers.

[CBear3]

https://clinicaltrials.gov/ct2/show/NCT ... w=2&rank=1

Clinical trial on if facemasks do reduce chance of getting covid.

Challenges when using facial masks outside the health care system include wearing the mask consistently, an efficacy of the mask of app. 8 hours necessitating a change of mask throughout the day, and that it is not sufficiently tight enough to safely keep the virus out. Moreover, the eyes (mucous membrane) remain exposed. Compliance could also be another challenge.

SARS-COV2 is assumed to primarily enter the body via the mouth through respiratory droplets - or possibly through inhalation of aerosol containing the virus. From the mouth the virus is assumed to spread to the airways and the gastro-intestinal tract. SARS-COV2 is also known to be transmitted via physical contact, helped along by the fact that the virus can survive on surfaces for at least 72 hours. Touching such a contaminated surface can transfer the virus to the mouth via the hand - and thus lead to infection of the person.

Facial masks are expected to protect against viral infection in two ways;

By reducing the risk of getting the virus in via the mouth or nose via respiratory droplets or aerosol
By reducing the transfer from virus-contaminated hands to the mouth or nose

If the clinical trial doesn't include virus being expelled through the mask, it's kind of worthless.

[grunthy]

can't make it mandatory but hopefully schools and daycares require it. And hospitals for health care workers.

They could make it mandatory to get a job, license, go to school, and etc.

[Dickie Dunn]

Needs to balance his weight better. Add something to the front of his basket like a cheating bobsledder.

[mikey]

"I'm gonna wait for science to tell me how we're gonna deal with this and get out of this...I don't care if it takes the rest of my life!"

[Science shows potential for ending this garbage]

"Hmmmm...I'll wait for some more negative science...I don't trust this kind."

Haha, I know I'm taking liberties, but it read exactly like that the first time through...it's perfectly on brand...

[NTP66]

Yeah, just gimme the vaccine. I want this to be over.

[MalkinIsMyHomeboy]

I was thinking today: how long do you think until "social distancing" will no longer be recommended?

[MrKennethTKangaroo]

I was thinking today: how long do you think until "social distancing" will no longer be recommended?

until there is either a cure or some good science saying it isnt necessary?

[grunthy]

I was thinking today: how long do you think until "social distancing" will no longer be recommended?

Vaccine, treatment, or cure.

[Troy Loney]

I was thinking today: how long do you think until "social distancing" will no longer be recommended?

until there is either a cure or some good science saying it isnt necessary?

Or until the case count is low enough to have effectively contained the spread.

[nocera]

"I'm gonna wait for science to tell me how we're gonna deal with this and get out of this...I don't care if it takes the rest of my life!"

[Science shows potential for ending this garbage]

"Hmmmm...I'll wait for some more negative science...I don't trust this kind."

Haha, I know I'm taking liberties, but it read exactly like that the first time through...it's perfectly on brand...

Is this about the vaccine uncertainty? Trust me, I get how it looks. I actually think it goes against my brand, to be honest.

I will trust that any vaccine that is allowed to be given to the masses is safe. I just want to make sure I'm on the up and up and know what I'm getting into. After the administration pushed a drug as a miracle cure before it went through testing, it isn't too much of a leap to think they could do the same with a vaccine. I'll put my trust in the scientists and doctors, not the administration.

[MalkinIsMyHomeboy]

but even if a vaccine is attained, it'll be some amount of time until that gets produced and distributed on a national/global scale and people actually start taking the vaccine

I was more thinking of "try to guess the date" rather than a more generic "when a vaccine is produced" answer