COVID-19

[King Colby]

I stand by these comments I made over the summer.

This may sound hyperbolic, but if an actual effective vaccine for this is deployed at any point before the end of 2021 it will be one of the greatest achievements in human history imo.

Granted, there's never been this kind of focused direction of resources and money towards developing a vaccine like we're seeing now. But I've never had had anything like a belief or expectation that we'd have a vax anytime before 2022. If we do, I said earlier that it will be one of the greatest achievements in human history.

If we have a safe and effective vaccine deployed next month, it will be nothing short of extraordinary.

Its so **** awesome.

[tifosi77]

I mean, load up a truck and drive up to mount Sinai. Work with their people to do the set up. Poke every employee. Go to the next place.

Do that with lots of trucks at lots of hospitals.

I really think we might be overestimating the complexity.

I think the hardest part is gathering and quickly analyzing the data to keep things heavily monitored, but that can be retrospective.

These candidate vaccines require extreme refrigeration, which is the major complicating factor.

[blackjack68]

Grunts says they’ve got it all figured out.

[NTP66]

Source of the post These candidate vaccines require extreme refrigeration, which is the major complicating factor.

Thought it was only the Pfizer one that did? Moderna's definitely doesn't require the extreme refrigeration.

[blackjack68]

Source of the post These candidate vaccines require extreme refrigeration, which is the major complicating factor.

Thought it was only the Pfizer one that did? Moderna's definitely doesn't require the extreme refrigeration.

Moderna requires temps consistent with a Chicken Pox vaccine.

Very common

[NTP66]

So normal refrigeration then.

[Nuge]

It would make sense to me to send the Pfizer one to major hospitals in cities and distribute from there since most of them have the storage capability (temperature-wise, maybe not volume-wise). The Moderna one could then be shipped to more rural areas since it can last longer at higher temps (at a CVS, Rite Aid, etc.). That being said, I have no idea how any of this stuff actually works. I'd just like to get one sooner than later.

[count2infinity]

Source of the post These candidate vaccines require extreme refrigeration, which is the major complicating factor.

Thought it was only the Pfizer one that did? Moderna's definitely doesn't require the extreme refrigeration.

Correct. Additionally there's another German company that are going into phase 3 trials that can survive at room temperature for either a week or a month. I think the former. And up to 3 or 6 months in normal refrigeration. Can't remember the exact numbers, but it's much more stable.

[King Colby]

Delivering frozen or refrigerated stuff isn't really a new concept. The harder part is long-term storage but thats not really a problem for right now considering it's highly likely that there is no excess inventory over the next few months (at least at the point of delivery).

Its not like CVS is going to have to have a solution in place to store their shot juice for a long period of time. At least not for a few months

[NTP66]

It would make sense to me to send the Pfizer one to major hospitals in cities and distribute from there since most of them have the storage capability (temperature-wise, maybe not volume-wise). The Moderna one could then be shipped to more rural areas since it can last longer at higher temps (at a CVS, Rite Aid, etc.). That being said, I have no idea how any of this stuff actually works. I'd just like to get one sooner than later.

Pfizer already has 4 states in mind initially:

Reuters reports Texas, New Mexico, Rhode Island and Tennessee were selected for the pilot program due to their size, population diversity, immunization infrastructure, and the need to reach people both in large cities and rural communities.

[grunthy]

Grunts says they’ve got it all figured out.

They already successfully delivered 2-3 experimental treatments in under 2 days from the EUA.

[nocera]

I can't be bothered to worry about distribution. The big worry was always that a vaccine could be not only created but then tested and approved as soon as possible. Now that it looks like that has happened, I am 100% confident that they will figure out the best way to distribute. I'm sure there will be hiccups and inefficiencies but it'll get done. And it'll still be done sooner than anybody originally expected.

[MrKennethTKangaroo]

Turn every vacant kmart into a giant walk in freezer

[grunthy]

https://www.google.com/amp/s/abcnews.go ... d=74183968

Big-box pharmacies like Walgreens and CVS say their facilities are fully equipped to store Pfizer's vaccine.

"All of our pharmacies are equipped with refrigerators and freezers that would allow us to store the vast majority of the vaccines right there," CVS Health's lead pharmacist and senior vice president, Chris Cox, told ABC News.

[King Colby]

Turn every vacant kmart into a giant walk in freezer

But then where would Rudy buy his hair dye?

[PFiDC]

At home depot like he has been

[King Colby]

At home depot like he has been

I thought he was more of a Four Seasons guy

[robbiestoupe]

Didn't somebody post something a while back that showed -80C is only necessary for long term storage (6+ months) but short term it can be lower? Not sure how accurate that was, but hopefully that's the case.

[grunthy]

Didn't somebody post something a while back that showed -80C is only necessary for long term storage (6+ months) but short term it can be lower? Not sure how accurate that was, but hopefully that's the case.

It can be stored for one week at a lower temperature.

[meow]

.

[meow]

Turn every vacant kmart into a giant walk in freezer

But then where would Rudy buy his hair dye?

[count2infinity]

[AuthorTony]

A very successful local businessman died from Covid today. 49 years old, 8 kids.

[Shyster]

BCG vaccination history associates with decreased SARS-CoV-2 seroprevalence across a diverse cohort of healthcare workers
https://www.jci.org/articles/view/145157

A study has found that the anti-tuberculosis Bacillus Calmette-Guérin vaccine is associated with decreased SARS-CoV-2 infection and seroconversion in a retrospective observational study of health-care workers. This may be another possible explanation for why Covid rates are low in many Asian countries. The vaccine pretty much standard in Japan, for example, but it's not very common in Europe or the US.

[King Colby]

Youyang gu is back for covid19-projections.com

Hes had a very accurate model (gave up forecasting on 10/5 because he got sick of it... estimated 231k total deaths by 11/1 and it ended up being 230,995).

No longer forecasting but has some algorithms to normalize all the data and his data appears to show a flattening of the curve so that's good news.

He also estimates THIRTY percent of people in the Dakotas have been infected. Highest in the country.